Laboratory biomarkers and frailty: presentation of the FRAILOMIC initiative.
نویسندگان
چکیده
*Corresponding author: Prof. Giuseppe Lippi, U.O. Diagnostica Ematochimica, Azienda Ospedaliero-Universitaria di Parma, Via Gramsci 14, 43126 Parma, Italy, Phone: + 39 0521 703050, Fax: + 39 0521 703791, E-mail: [email protected]; [email protected] . http://orcid.org/0000-0001-9523-9054 Pidder Jansen-Duerr: Research Institute for Biomedical Ageing Research, Universit ä t Innsbruck, Innsbruck, Austria Jose Vi ñ a: Facultad Medicina y Odontologia, Universidad de Valencia, Valencia, Spain Anna Durrance-Bagale: Niche Science and Technology Ltd., Richmond, UK Imad Abugessaisa, David Gomez-Cabrero and Jesper Tegn é r: Unit of Computational Medicine, Karolinska Institutet, Stockholm, Sweden Johannes Grillari: Evercyte GmbH, Vienna, Austria ; and University of Natural Resources and Life Sciences, Vienna, Austria Jorge Erusalimsky: Cardiff School of Health Sciences, Cardiff Metropolitan University, Cardiff, UK Alan Sinclair: Department of Stroke Medicine, Luton and Dunstable University Hospital, Luton, UK Leocadio Rodriguez-Man ã s: Division of Geriatrics, Hospital Universitario de Getafe, Getafe, Spain Letter to the Editor
منابع مشابه
In Search of 'Omics'-Based Biomarkers to Predict Risk of Frailty and Its Consequences in Older Individuals: The FRAILOMIC Initiative.
An increase in the number of older people experiencing disability and dependence is a critical aspect of the demographic change that will emerge within Europe due to the rise in life expectancy. In this scenario, prevention of these conditions is crucial for the well-being of older citizens and for the sustainability of our healthcare systems. Thus, the diagnosis and management of conditions li...
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BACKGROUND The immune and blood coagulation systems have been implicated in the pathophysiology of the geriatric syndrome of frailty, but limited prospective data examining the relationship of clotting/inflammation biomarkers to risk of incident frailty exist. METHODS This prospective analysis was derived from a nested case-control study within the Women's Health Initiative. Among women 65 to...
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Frailty is a relatively young area of investigation in cardiovascular research. The first wave of published research, circa 2001 to 2006, uncovered the epidemiological and pathophysiological links between frailty and cardiovascular disease (CVD). Compared to those without CVD, older adults with CVD were reported to have an odds ratio of 2.7 to 4.1 for prevalent frailty in cross-sectional studie...
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ورودعنوان ژورنال:
- Clinical chemistry and laboratory medicine
دوره 53 10 شماره
صفحات -
تاریخ انتشار 2015